Wednesday, April 2, 2025
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Groundbreaking Breakthrough in MS Monitoring: Quantum BioPharma Teams Up with Massachusetts General Hospital for Clinical Study!

Quantum BioPharma (NASDAQ: QNTM) just dropped major news — a clinical partnership with Massachusetts General Hospital (MGH) that could revolutionize how Multiple Sclerosis (MS) is monitored and treated.

Here’s a simplified breakdown of the announcement and why it matters:


🔬 The Big News

  • Quantum BioPharma is launching a joint clinical study with scientists from MGH (a Harvard-affiliated hospital).
  • The study focuses on a new PET imaging technique using a tracer called [18F]3F4AP to detect demyelinationin MS patients — a hallmark of the disease.

🧠 What’s Demyelination & Why It Matters

  • MS damages the myelin sheath, a protective coating around nerve fibers.
  • Tracking demyelination is key for understanding MS progression and treatment response.
  • The new PET scan could visually and quantitatively detect this damage — much more sensitively than traditional MRIs.

🧪 About the Study

  • Led by Dr. Pedro Brugarolas (MGH/Harvard Radiology) and Dr. Eric Klawiter (MGH Neurology).
  • Participants will undergo both PET scans with [18F]3F4AP and traditional MRIs.
  • The PET tracer is a modified version of dalfampridine, a drug that binds to potassium channels in demyelinated axons.
  • Goal: Determine how effective this method is at tracking disease progression and treatment responses in MS.

💡 Why This Is a Game-Changer

  • Could transform MS diagnostics by offering clearer, earlier detection of damage.
  • Aids development of remyelinating and neuroprotective therapies, including Quantum’s own Lucid-MScompound.
  • Lucid-MS has already shown myelin protection and regeneration in animal studies.

🧬 Quantum’s Bigger Vision

  • Focused on neurodegenerative, metabolic, and alcohol misuse disorders.
  • Lead candidate Lucid-MS aims to halt or reverse myelin loss in MS.
  • Also owns 25.71% of Celly Nutrition Corp., makers of UNBUZZD™, a product for alcohol misuse recovery.

📢 Key Quotes

  • Dr. Chruscinski (Quantum VP): “This PET biomarker could become essential in future MS trials.”
  • Zeeshan Saeed (CEO): “Excited to collaborate with MGH’s brilliant minds.”
  • Dr. Brugarolas (MGH): “[18F]3F4AP may help identify patients who respond to new MS treatments.”

📈 Final Take

This collaboration positions Quantum BioPharma at the cutting edge of MS treatment innovation, combining elite scientific minds with biotech ambition. If successful, it could redefine how MS is tracked and treated — a win for patients, doctors, and investors alike.

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